Just wipe the HDD.
The MineOS Tunrkey ISO should have all the drivers you need included.
Another path is ignoring the ISO, and go to (for example) ubuntu:
http://www.ubuntu.com/download/desktop.
The Ubuntu ISO should have most drivers included or available
Then install MineOS on top of that: HOW TO: install MINEOS-NODE on UBUNTU SERVER 14.04.2 (this is for Ubuntu server, but it should be more or less the same method for Ubuntu desktop)
I’d reccomend going the MineOS Turnkey 32bit way first though.